PF3D7_0113800

Function and Localization

Product Description: DBL containing protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: N/A

Curated GO (PlasmoDB):

Expression by stage, third quartile (Malaria Cell Atlas): No data

More info:

• Malaria Parasite Metabolic Pathways (MPMP) Link
• BiGG Metabolic Model Link
• STRING Interaction Network Link

Essentiality

Zhang Phenotype: Mutable in CDS

• Mutagenesis Index Score (MIS): 1
• Mutagenesis Fitness Score (MFS): -2.076
• Number of insertions in CDS: 9

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: N/A

"Best" AlphaFill ligand hit: No AlphaFill hits

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_104345

No human ortholog(s)

Protein Information

Protein length: 2900 | Molecular Weight (kDa): 346.566

UniProt ID(s): A0A159SJ85, A0A159SK04, A0A159SKC3, A0A5P0ZZX3, A0A5P1A081, A0A5P1A0L6, A0A5P1A0N7, A0A5P1A1F3, A0A5P1A2U2, Q8I2E0, Q9U4X0

PDB ID(s): None

Isoelectric Point: 5.09

Protein Domain Annotations:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0113800

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

Any inclusion in genotype call

PlasmoDB Total SNPs: 1277

Non-coding: 262 | Synonymous: 264 | Nonsynonymous: 742 | Stop Codon: 9

Associated Publications