PF3D7_0306600 (ATPTG17)

Function and Localization

Product Description: ATP synthase-associated protein, putative

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: N/A

Curated GO (PlasmoDB):

Expression by stage, third quartile (Malaria Cell Atlas): No data

More info:

• Malaria Parasite Metabolic Pathways (MPMP) Link
• BiGG Metabolic Model Link
• STRING Interaction Network Link

Essentiality

Zhang Phenotype: Non - Mutable in CDS *tentative

• Mutagenesis Index Score (MIS): 0.119
• Mutagenesis Fitness Score (MFS): -3.029
• Number of insertions in CDS: 0

PlasmoGEM Phenotype: Dispensable (Pb ortholog: PBANKA_0405000)

• Relative Growth Rate: 0.90 ± 0.13
• Confidence: 5.42

RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_0405000)

• Gene Modification: Disrupted
• RMgmDB ID Link: RMgm-1854

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: Q9NLB1

"Best" AlphaFill ligand hit: No AlphaFill hits

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_139497

No human ortholog(s)

Protein Information

Protein length: 85 | Molecular Weight (kDa): 9.949

UniProt ID(s): Q9NLB1

PDB ID(s): None

Isoelectric Point: 10.54

Protein Domain Annotations:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0306600

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 48

Non-coding: 43 | Synonymous: 5 | Nonsynonymous: 0 | Stop Codon: 0

Associated Publications