Genomic location: Pf3D7_05_v3:555,264..556,651(+)
Miles Classification: Core
Product Description: conserved protein, unknown function
SignalP Peptide: MNFVFIYIVLISFFNKSRC
# Transmembrane Domains: 0
EC Numbers: N/A
Curated GO (PlasmoDB):
N/AExpression by stage, third quartile (Malaria Cell Atlas): No data
More info:
Zhang Phenotype: Non - Mutable in CDS
PlasmoGEM Phenotype: Dispensable (Pb ortholog: PBANKA_1112700)
RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_1112700)
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8I3X7
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
Protein length: 269 | Molecular Weight (kDa): 31.039
UniProt ID(s): Q8I3X7
PDB ID(s): None
Isoelectric Point: 6.75
Protein Domain Annotations:
| InterPro | N/A | N/A |
| PFam | N/A | N/A |
| Superfamily | N/A | N/A |
Old (Pf3D7v3) Gene ID: PF3D7_0513000
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
| variant type | common | rare | doubleton | singleton |
|---|---|---|---|---|
| synonymous | 1 | 12 | 5 | 14 |
| disruptive | 1 | 7 | 8 | 17 |
| missense | 1 | 7 | 7 | 16 |
Any inclusion in genotype call
| variant type | common | rare | doubleton | singleton |
|---|---|---|---|---|
| synonymous | 3 | 23 | 4 | 18 |
| disruptive | 3 | 22 | 12 | 42 |
| missense | 2 | 17 | 9 | 33 |
PlasmoDB Total SNPs: 45
Non-coding: 40 | Synonymous: 5 | Nonsynonymous: 0 | Stop Codon: 0
| PMID | Title | Authors | DOI |
|---|---|---|---|
| 12368867 | Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. | Hall N, Pain A, ..., Barrell BG | 10.1038/nature01095 |