Genomic location: Pf3D7_05_v3:1,002,547..1,008,230(+)
Miles Classification: Core
Product Description: conserved Plasmodium protein, unknown function
SignalP Peptide: N/A
# Transmembrane Domains: 0
EC Numbers: N/A
Curated GO (PlasmoDB):
N/AExpression by stage, third quartile (Malaria Cell Atlas):
Ring: 2.40 | Trophozoite: 2.14 | Schizont: 0 | Gametocyte: 1.81
More info:
Zhang Phenotype: Non - Mutable in CDS
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8I3M4
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
Protein length: 1243 | Molecular Weight (kDa): 147.819
UniProt ID(s): Q8I3M4
PDB ID(s): None
Isoelectric Point: 8.25
Protein Domain Annotations:
InterPro | N/A | N/A |
PFam | N/A | N/A |
Superfamily | SSF101908 | N/A |
Old (Pf3D7v3) Gene ID: PF3D7_0524100
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 12 | 65 | 51 | 82 |
disruptive | 71 | 221 | 119 | 281 |
missense | 48 | 196 | 100 | 235 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 21 | 132 | 58 | 98 |
disruptive | 122 | 470 | 215 | 424 |
missense | 80 | 372 | 177 | 250 |
PlasmoDB Total SNPs: 306
Non-coding: 142 | Synonymous: 85 | Nonsynonymous: 79 | Stop Codon: 0
PMID | Title | Authors | DOI |
---|---|---|---|
12368867 | Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. | Hall N, Pain A, ..., Barrell BG | 10.1038/nature01095 |