About Gene List Toggle Layout

PF3D7_0608200

Genomic location: Pf3D7_06_v3:341,804..342,871(-)

Miles Classification: Core

Function and Localization

Product Description: conserved Plasmodium protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: N/A

Curated GO (PlasmoDB):

N/A

Expression by stage, third quartile (Malaria Cell Atlas): No data

More info:

Essentiality

Zhang Phenotype: Non - Mutable in CDS *tentative

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: C6KST0

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_532729

No human ortholog(s)

Protein Information

Protein length: 156 | Molecular Weight (kDa): 19.116

UniProt ID(s): C6KST0

PDB ID(s): None

Isoelectric Point: 10.18

Protein Domain Annotations:

InterPro N/A N/A
PFam N/A N/A
Superfamily N/A N/A

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0608200

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type common rare doubleton singleton
synonymous 3 10 2 7
disruptive 2 9 5 17
missense 2 8 5 16

Any inclusion in genotype call

variant type common rare doubleton singleton
synonymous 6 15 3 10
disruptive 5 29 20 41
missense 3 20 18 25

PlasmoDB Total SNPs: 71

Non-coding: 61 | Synonymous: 6 | Nonsynonymous: 4 | Stop Codon: 0

Associated Publications

PMID Title Authors DOI
12368867 Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Hall N, Pain A, ..., Barrell BG 10.1038/nature01095