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PF3D7_1023300

Genomic location: Pf3D7_10_v3:983,518..985,785(-)

Miles Classification: Core

Function and Localization

Product Description: conserved protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 1

EC Numbers: N/A

Curated GO (PlasmoDB):

Component GO:0020011 apicoplast

Expression by stage, third quartile (Malaria Cell Atlas): No data

More info:

Essentiality

Zhang Phenotype: Non - Mutable in CDS *tentative

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: Q8IJH2

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_151672

No human ortholog(s)

Protein Information

Protein length: 79 | Molecular Weight (kDa): 9.384

UniProt ID(s): Q8IJH2

PDB ID(s): None

Isoelectric Point: 8.77

Protein Domain Annotations:

InterPro N/A N/A
PFam N/A N/A
Superfamily N/A N/A

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_1023300

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 139

Non-coding: 138 | Synonymous: 1 | Nonsynonymous: 0 | Stop Codon: 0

Associated Publications

PMID Title Authors DOI
12368864 Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, Hall N, ..., Barrell B 10.1038/nature01097
12368868 Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14. Gardner MJ, Shallom SJ, ..., Fraser CM 10.1038/nature01094
30212465 Integrative proteomics and bioinformatic prediction enable a high-confidenceapicoplast proteome in malaria parasites. Boucher MJ, Ghosh S, ..., Yeh E 10.1371/journal.pbio.2005895