Genomic location: Pf3D7_12_v3:962,262..968,275(-)
Miles Classification: Core
Product Description: conserved Plasmodium protein, unknown function
SignalP Peptide: N/A
# Transmembrane Domains: 2
EC Numbers: N/A
Curated GO (PlasmoDB):
N/AExpression by stage, third quartile (Malaria Cell Atlas): No data
More info:
Zhang Phenotype: Non - Mutable in CDS
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8I5I1
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
Protein length: 1560 | Molecular Weight (kDa): 188.237
UniProt ID(s): A0A143ZZX1, Q8I5I1
PDB ID(s): None
Isoelectric Point: 8.12
Protein Domain Annotations:
InterPro | N/A | N/A |
PFam | N/A | N/A |
Superfamily | N/A | N/A |
Old (Pf3D7v3) Gene ID: PF3D7_1223600
Resistome Missense Mutations: S332N, D566E
Resistome Compounds with Missense Mutations: AN13762, AN13956, MMV982556
Resistome # Samples with Disruptive Mutations: 6 (6 missense, 0 "interesting" missense)
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 7 | 53 | 27 | 75 |
disruptive | 31 | 176 | 88 | 256 |
missense | 23 | 158 | 83 | 216 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 14 | 104 | 51 | 77 |
disruptive | 77 | 399 | 207 | 442 |
missense | 44 | 307 | 171 | 306 |
PlasmoDB Total SNPs: 212
Non-coding: 117 | Synonymous: 52 | Nonsynonymous: 42 | Stop Codon: 1
PMID | Title | Authors | DOI |
---|---|---|---|
12368864 | Genome sequence of the human malaria parasite Plasmodium falciparum. | Gardner MJ, Hall N, ..., Barrell B | 10.1038/nature01097 |