Genomic location: Pf3D7_13_v3:230,753..231,760(+)
Miles Classification: Core
Product Description: conserved Plasmodium protein, unknown function
SignalP Peptide: N/A
# Transmembrane Domains: 0
EC Numbers: N/A
Curated GO (PlasmoDB):
Component | GO:0020011 | apicoplast |
Expression by stage, third quartile (Malaria Cell Atlas): No data
More info:
Zhang Phenotype: Non - Mutable in CDS
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8IES2
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
Protein length: 213 | Molecular Weight (kDa): 25.736
UniProt ID(s): Q8IES2
PDB ID(s): None
Isoelectric Point: 9.66
Protein Domain Annotations:
InterPro | N/A | N/A |
PFam | N/A | N/A |
Superfamily | N/A | N/A |
Old (Pf3D7v3) Gene ID: PF3D7_1304300
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 2 | 17 | 6 | 14 |
disruptive | 6 | 22 | 16 | 31 |
missense | 5 | 16 | 12 | 28 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 4 | 26 | 6 | 12 |
disruptive | 11 | 51 | 24 | 44 |
missense | 8 | 36 | 17 | 28 |
PlasmoDB Total SNPs: 36
Non-coding: 14 | Synonymous: 11 | Nonsynonymous: 11 | Stop Codon: 0
PMID | Title | Authors | DOI |
---|---|---|---|
30212465 | Integrative proteomics and bioinformatic prediction enable a high-confidenceapicoplast proteome in malaria parasites. | Boucher MJ, Ghosh S, ..., Yeh E | 10.1371/journal.pbio.2005895 |