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PF3D7_1339300

Genomic location: Pf3D7_13_v3:1,579,733..1,585,346(+)

Miles Classification: Core

Function and Localization

Product Description: conserved protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: N/A

Curated GO (PlasmoDB):

Component GO:0005634 nucleus

Expression by stage, third quartile (Malaria Cell Atlas):

Ring: 0.91 | Trophozoite: 1.24 | Schizont: 0 | Gametocyte: 0

More info:

Essentiality

Zhang Phenotype: Non - Mutable in CDS

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: A0A5K1K8I2

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_194384

No human ortholog(s)

Protein Information

Protein length: 275 | Molecular Weight (kDa): 31.396

UniProt ID(s): A0A5K1K8I2

PDB ID(s): None

Isoelectric Point: 7.68

Protein Domain Annotations:

InterPro N/A N/A
PFam N/A N/A
Superfamily N/A N/A

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_1339300

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 416

Non-coding: 405 | Synonymous: 8 | Nonsynonymous: 3 | Stop Codon: 0

Associated Publications

PMID Title Authors DOI
16267556 A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, Vignali M, ..., Hughes RE 10.1038/nature04104
23181666 Organellar proteomics reveals hundreds of novel nuclear proteins in the malariaparasite Plasmodium falciparum. Oehring SC, Woodcroft BJ, ..., Voss TS 10.1186/gb-2012-13-11-r108