Genomic location: Pf3D7_13_v3:2,701,228..2,704,776(+)
Miles Classification: Core
Product Description: secreted ookinete protein, putative
SignalP Peptide: MKLNTLISFFSFVCLFFRVLSC
# Transmembrane Domains: 0
EC Numbers: N/A
Curated GO (PlasmoDB):
N/AExpression by stage, third quartile (Malaria Cell Atlas): No data
More info:
Zhang Phenotype: Mutable in CDS
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_1143700)
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8ID30
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersOrthology to BindingDB Entries:
P37840 | Alpha-synuclein | OrthoMCL BLAST | US9085549, 52US9085549, 53US9085549, 54US9085549, 55... |
Protein length: 1182 | Molecular Weight (kDa): 135.834
UniProt ID(s): Q8ID30
PDB ID(s): None
Isoelectric Point: 4.39
Protein Domain Annotations:
InterPro | N/A | N/A |
PFam | N/A | N/A |
Superfamily | N/A | N/A |
Old (Pf3D7v3) Gene ID: PF3D7_1367800
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 15 | 52 | 33 | 65 |
disruptive | 85 | 215 | 110 | 243 |
missense | 46 | 147 | 83 | 169 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 22 | 99 | 35 | 80 |
disruptive | 142 | 374 | 135 | 268 |
missense | 75 | 263 | 102 | 170 |
PlasmoDB Total SNPs: 294
Non-coding: 0 | Synonymous: 156 | Nonsynonymous: 138 | Stop Codon: 0
No associated publications