About Gene List Toggle Layout

PF3D7_1367800 (PSOP2)

Genomic location: Pf3D7_13_v3:2,701,228..2,704,776(+)

Miles Classification: Core

Function and Localization

Product Description: secreted ookinete protein, putative

SignalP Peptide: MKLNTLISFFSFVCLFFRVLSC

# Transmembrane Domains: 0

EC Numbers: N/A

Curated GO (PlasmoDB):

N/A

Expression by stage, third quartile (Malaria Cell Atlas): No data

More info:

Essentiality

Zhang Phenotype: Mutable in CDS

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_1143700)

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: Q8ID30

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

Orthology to BindingDB Entries:

P37840 Alpha-synuclein OrthoMCL BLAST US9085549, 52US9085549, 53US9085549, 54US9085549, 55...

Orthology Information

Ortholog Group (OrthoMCL): OG6_111908

No human ortholog(s)

Protein Information

Protein length: 1182 | Molecular Weight (kDa): 135.834

UniProt ID(s): Q8ID30

PDB ID(s): None

Isoelectric Point: 4.39

Protein Domain Annotations:

InterPro N/A N/A
PFam N/A N/A
Superfamily N/A N/A

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_1367800

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type common rare doubleton singleton
synonymous 15 52 33 65
disruptive 85 215 110 243
missense 46 147 83 169

Any inclusion in genotype call

variant type common rare doubleton singleton
synonymous 22 99 35 80
disruptive 142 374 135 268
missense 75 263 102 170

PlasmoDB Total SNPs: 294

Non-coding: 0 | Synonymous: 156 | Nonsynonymous: 138 | Stop Codon: 0

Associated Publications

No associated publications