Genomic location: Pf3D7_13_v3:2,683,581..2,684,967(+)
Miles Classification: Core
Product Description: CLAMP domain-containing protein, putative
SignalP Peptide: N/A
# Transmembrane Domains: 0
EC Numbers: N/A
Curated GO (PlasmoDB):
N/AExpression by stage, third quartile (Malaria Cell Atlas): No data
More info:
Zhang Phenotype: Mutable in CDS
PlasmoGEM Phenotype: Dispensable (Pb ortholog: PBANKA_1143100)
RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_1143100)
More info: PhenoPlasm Link
AlphaFill Uniprot ID: C0H5L0
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
Ortholog Group (OrthoMCL): OG6_106153
Most Similar Human Ortholog: F5H7A8
All Human Orthologs (OrthoMCL):
ENSG00000196118 | coiled-coil domain containing 189 |
Protein length: 367 | Molecular Weight (kDa): 44.642
UniProt ID(s): C0H5L0
PDB ID(s): None
Isoelectric Point: 9.69
Protein Domain Annotations:
InterPro | IPR032727 | Flagellar C1a complex subunit C1a-32 |
PFam | PF14769 | Flagellar C1a complex subunit C1a-32 |
Superfamily | N/A | N/A |
Old (Pf3D7v3) Gene ID: PF3D7_1367200
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 3 | 25 | 17 | 24 |
disruptive | 6 | 61 | 32 | 80 |
missense | 6 | 60 | 32 | 74 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 9 | 49 | 13 | 27 |
disruptive | 20 | 118 | 58 | 80 |
missense | 17 | 106 | 51 | 71 |
PlasmoDB Total SNPs: 54
Non-coding: 34 | Synonymous: 12 | Nonsynonymous: 8 | Stop Codon: 0
No associated publications